Identification and Characterization of ZEL-H16 as a Novel Agonist of the Histamine H3 Receptor
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چکیده
منابع مشابه
Identification and Characterization of ZEL-H16 as a Novel Agonist of the Histamine H3 Receptor
The histamine H3 receptor (H3R) has been recognized as a promising target for the treatment of various central and peripheral nervous system diseases. In this study, a non-imidazole compound, ZEL-H16, was identified as a novel histamine H3 receptor agonist. ZEL-H16 was found to bind to human H3R with a Ki value of approximately 2.07 nM and 4.36 nM to rat H3R. Further characterization indicated ...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0042185